Immunology for Medical Students
Höfundur: Matthew Helbert
3.990 kr.
Lýsing:
Comprehensive yet concise and easy to read, this updated edition of Immunology for Medical Students effectively explains complex immunology topics and their relevance in clinical practice. Boasting just the right amount of detail for today's busy medical student, it delivers state-of-the-art coverage of the latest scientific and clinical knowledge in the field. Detailed and explanatory illustrations, combined with clinically relevant examples and cases, offer a unique understanding of the human immune system and its role in protecting us from disease.
Annað
- Höfundur: Matthew Helbert
- Útgáfa:3
- Útgáfudagur: 062016
- Blaðsíður: 344
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- Format:ePub
- ISBN 13: 9780702068010
- ISBN 10: 0702068012
Efnisyfirlit
- Cover image
- Title Page
- Table of Contents
- Copyright
- Preface
- ▪ Preface to the Third Edition
- ▪ Preface to the Second Edition
- ▪ Preface to the First Edition
- Acknowledgments
- How to Use This Book
- Icons
- Microorganisms Mentioned in This Book
- Section I Introduction
- Chapter 1 Introduction to the Immune System
- Can You Now …
- Chapter 2 Basic Concepts and Components of the Immune System
- ▪ Innate Immunity
- ▪ Adaptive Immunity
- ▪ Components of the Immune System
- ▪ Active and Passive Immunity
- ▪ Phases of an Immune Response
- ▪ Types of Immune Response
- Can You Now…
- Chapter 1 Introduction to the Immune System
- Chapter 3 Introduction to Antigen Recognition
- Antigen Recognition Molecules
- B-Cell and T-Cell Receptors
- Major Histocompatibility Complex Molecules
- Can You Now …
- Chapter 4 Antigens and Antibody Structure
- ▪ Antigens
- ▪ Antibodies
- Can You Now…
- Chapter 5 Antibody-Antigen Interaction
- ▪ Antigen-Binding Sites of Antibodies
- ▪ Diagnostic Tests for Antibody or Antigen
- Can You Now….
- Chapter 6 Antibody Diversity
- ▪ Immunoglobulin Genes
- ▪ Immunoglobulin Classes
- Can You Now…
- Chapter 7 The T-Cell Receptor
- ▪ Structure of the T-Cell Receptor
- ▪ Generation of Diversity of the T-Cell Receptor Genes
- ▪ Recognition of Antigen
- ▪ Other Accessory Molecules Involved in T-Cell Function
- Can You Now…
- Chapter 8 Major Histocompatibility Complex
- ▪ Genetic Organization
- ▪ Regulation of Gene Expression
- ▪ Structure of the Major Histocompatibility Complex Gene Products
- ▪ Restriction of Antigen Recognition
- ▪ Population Advantages of Polymorphism in the Major Histocompatibility Complex
- ▪ Disease Correlations
- Can You Now …
- Chapter 9 Review of Antigen Recognition
- ▪ Important Structural Features
- ▪ Generation of Diversity
- Chapter 10 Antigen Processing and Presentation
- Pathways of Antigen Processing
- Mechanisms of Antigen Processing
- Evasion of Processing Pathways by Pathogens
- Can You Now …
- Chapter 11 Lymphocyte Activation
- Antigen Receptors
- Signaling Events
- Amplification Through Signaling Pathways
- Response
- Can You Now …
- Chapter 12 Hematopoiesis
- Three Major Stages of Hematopoiesis
- Lymphoid Cells
- Myeloid Cells
- Can You Now …
- Chapter 13 Organs and Tissues of the Immune System
- ▪ Primary and Secondary Lymphoid Organs
- ▪ Lymphocyte Trafficking
- Can You Now…
- Chapter 14 B-Cell Development
- ▪ Early B-Lymphocyte Development
- ▪ The Mature B Cell
- ▪ Somatic Mutation and Class Switching in Germinal Centers
- ▪ Thymus-Independent Antigens
- ▪ B1 B Cells and Natural Antibodies
- Can You Now…
- Chapter 15 T-Cell Development
- ▪ The Thymus
- ▪ The Periphery: Naive T-Cell Activation by Antigen
- Can You Now …
- Chapter 16 T-Cell Interactions and T-Cell Help
- ▪ Generation of Stimulated, or Primed, B and T Cells
- ▪ Generation of Effector Cells
- ▪ Providing the Most Appropriate Immune Response for a Given Pathogen
- Can You Now…
- Chapter 17 Immunologic Memory and Homeostasis
- ▪ Long-Term Immunologic Memory
- ▪ Lymphocyte Homeostasis
- ▪ Apoptosis
- Can You Now …
- Chapter 18 Regulation of the Immune System
- ▪ Tolerance
- Can You Now…
- Chapter 19 Brief Review of Immune Physiology
- ▪ Integrated Immune System: Connections Between Adaptive and Innate Responses
- Chapter 20 Constitutive Defenses Including Complement
- Barriers to Infection
- Extracellular Molecules of the Innate Immune System
- Can You Now …
- Chapter 21 Phagocytes
- ▪ Phagocytic Cell Types
- ▪ Phagocyte Production
- ▪ Phagocyte Recruitment
- ▪ Receptors on Phagocytes
- ▪ Molecular Patterns
- ▪ Actions of Phagocytes
- ▪ Phagocyte Defects
- ▪ Molecular Recognition by the Innate and Adaptive Immune Systems
- Can You Now…
- Chapter 22 Killing in the Immune System
- ▪ Response to Parasite Worms
- ▪ Mast Cells
- ▪ Natural Killer Cells
- ▪ Intracellular Mechanisms of Apoptosis
- Can You Now…
- Chapter 23 Inflammation
- ▪ Types of Inflammation
- ▪ Cytokine Network in Inflammation
- ▪ Tuberculosis
- ▪ Hepatitis B Infection
- ▪ “Overzealous” Inflammation
- Can You Now…
- Chapter 24 Cytokines in the Immune System
- ▪ Overview
- ▪ Cytokine Receptors and Signaling Molecules
- ▪ Review of Some of the Roles of Cytokines in Immune Responses
- ▪ Clinical Uses for Cytokines and Cytokine Blockade
- Can You Now…
- Chapter 25 Infections and Vaccines
- ▪ How Organisms Evade the Immune Response
- ▪ Mechanisms of Immunity
- ▪ Types of Vaccines
- ▪ Vaccine Schedules
- Can You Now…
- Chapter 26 Hypersensitivity Reactions
- ▪ Types of Triggers for Hypersensitivity
- ▪ Types Of Hypersensitivity Reaction
- ▪ Diagnosis and Treatment of Hypersensitivity
- Can You Now…
- Chapter 27 Immediate Hypersensitivity (Type I)
- ▪ Definitions
- ▪ Allergen
- ▪ Degranulating Cells
- ▪ Antibody
- ▪ T-Helper 2 Cells
- ▪ Predisposition to Allergy
- ▪ Mediators of Early Phase of Allergy
- ▪ Mediators of Late Phase of Allergy
- ▪ Treatment
- Can You Now…
- Chapter 28 How Autoimmune Disease Develops
- ▪ Some Autoimmunity is Normal
- ▪ Initiation of Autoimmune Disease
- ▪ T-Cell Tolerance
- ▪ Breakdown of T-Cell Tolerance
- ▪ Tests for Autoimmune Disease
- Can You Now…
- Chapter 29 Antibody-Mediated Hypersensitivity (Type II)
- ▪ Immune-Mediated Hemolysis
- ▪ Type II Hypersensitivity and Antibodies That Affect Cell Function
- Can You Now…
- Chapter 30 Immune Complex Disease (Type III Hypersensitivity)
- ▪ Antigens in Immune Complexes
- ▪ Antibodies in Immune Complexes
- ▪ Clearance of Immune Complexes
- ▪ Mechanisms of Inflammation in Immune Complex Disease
- ▪ Immune Complex Disease in the Kidney
- ▪ Treatment of Immune Complex Disease
- Can You Now …
- Chapter 31 Delayed Hypersensitivity (Type IV) and Review of Hypersensitivity Reactions
- ▪ Delayed Hypersensitivity Reactions are Driven by T-Helper 1 Cells
- ▪ Type IV Hypersensitivity Disease
- Can You Now …
- Chapter 32 Primary Immunodeficiency
- ▪ Infections Provide Clues to the Type of Immunodeficiency
- ▪ Causes of Primary Immunodeficiency
- ▪ Screening for Severe Combined Immune Deficiency
- ▪ Diagnosis of Primary Immunodeficiency
- ▪ Treatment
- Can You Now…
- Chapter 33 Secondary Immunodeficiency
- ▪ HIV Infection
- ▪ Other Secondary Immunodeficiencies
- Can You Now…
- Chapter 34 Transplantation
- ▪ Transplantation Terminology
- ▪ Solid Organ Transplantation
- ▪ Stem Cell Transplantation
- ▪ Tissue-Typing Techniques
- ▪ Immunosuppressive Drugs
- ▪ Xenotransplantation
- Can You Now …
- Chapter 35 Tumor Immunology
- ▪ Lymphoid Tumors
- ▪ Immunity to Tumors
- Can You Now…
- Chapter 36 Biopharmaceuticals
- ▪ Monoclonal Antibodies
- ▪ Recombinant Cytokines
- Can You Now…
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- Gerð : 208
- Höfundur : 8789
- Útgáfuár : 2016
- Leyfi : 380