Efnisyfirlit

• Cover
• Introduction
  • About This Book
  • Conventions Used in This Book
  • Foolish Assumptions
  • How This Book Is Organized
  • Icons Used in This Book
  • Beyond This Book
  • Where to Go from Here
• Part 1: The Lowdown on Genetics: Just the Basics
  • Chapter 1: Welcome to Genetics: What’s What and Who’s Who
    • What Is Genetics?
    • Genetics as a Career
  • Chapter 2: Basic Cell Biology
    • Looking Around Your Cell
    • Mitosis: Splitting Up
    • Meiosis: Making Cells for Reproduction
  • Chapter 3: Visualize Peas: Discovering the Laws of Inheritance
    • Gardening with Gregor Mendel
    • Speaking the Language of Inheritance
    • Simplifying Inheritance
    • Finding Unknown Alleles
    • Applying Basic Probability to the Likelihood of Inheritance
    • Solving Simple Genetics Problems
  • Chapter 4: Law Enforcement: Mendel’s Laws Applied to Complex Traits
    • Dominant Alleles Rule … Sometimes
    • Alleles Causing Complications
    • Making Life More Complicated
    • Uncovering More Exceptions to Mendel’s Laws
• Part 2: DNA: The Genetic Material
  • Chapter 5: DNA: The Basis of Life
    • Chemical Ingredients of DNA
    • Examining Different Varieties of DNA
    • Digging into the History of DNA
  • Chapter 6: Chromosomes: The Big Picture
    • Deconstructing the Double Helix
    • Anatomy of a Chromosome
    • Two Chromosomes Are Better than One (or Three)
    • Sex Chromosomes: Is It a Boy or Girl?
  • Chapter 7: Replication: A Copy Machine for DNA
    • Unzipped: Creating the Pattern for More DNA
    • How DNA Copies Itself
    • Replication in Eukaryotes
    • How Circular DNAs Replicate
  • Chapter 8: DNA Sequencing: Decoding the Genome
    • Sequencing: Reading the Language of DNA
    • Sequencing Your Way to the Human Genome
    • Trying on a Few Genomes
  • Chapter 9: RNA: DNA’s Close Cousin
    • You Already Know a Lot about RNA
    • Transcription: Copying DNA’s Message into RNA’s Language
    • Post-transcription Processing
  • Chapter 10: Translating the Genetic Code
    • Discovering the Good in a Degenerate
    • Meeting the Translating Team
    • Taking the Translation Trip
    • Proteins Are Precious Polypeptides
  • Chapter 11: Gene Expression: What a Cute Pair of Genes
    • Getting Your Genes Under Control
    • To Be Expressed or Not To Be Expressed?
    • Regulating Gene Expression: A Time and Place for Everything
    • Controlling Transcription Before It Starts
    • Regulation of Gene Transcription: Flipping the Switch
    • Retroactive Control: Things That Happen after Transcription
    • Gene Control Lost in Translation
    • Prokaryotic Gene Expression
• Part 3: Genetics and Your Health
  • Chapter 12: When Things Go Wrong: Changes in DNA Sequence
    • Heritable or Not Heritable?
    • Facing the Consequences of Sequence Variants
    • Sorting Out Terminology
    • What Causes Sequence Variants?
    • Evaluating Options for DNA Repair
  • Chapter 13: Chromosome Disorders: It’s All a Numbers Game
    • Chromosome Numbers: No More and No Less
    • Aneuploidy of the Autosomal Chromosomes
    • Aneuploidy of the Sex Chromosomes
    • Exploring Variations in Chromosome Structure
    • How Chromosomes Are Studied
    • Non-Invasive Prenatal Testing for Aneuploidy
  • Chapter 14: Taking a Closer Look at the Genetics of Cancer
    • Defining Cancer
    • Recognizing Cancer as a DNA Disease
    • Breaking Down the Types of Cancers
  • Chapter 15: Genetic Counseling, Risk Assessment, and Genetic Testing
    • Getting to Know Genetic Counselors
    • Building and Analyzing a Family Tree
    • Autosomal Inheritance: No Differences Among the Sexes
    • Found on Sex Chromosomes: Sex-linked Inheritance
    • Testing for Genetic Disorders
  • Chapter 16: Treating Genetic Disorders and Using Genetics to Tailor Treatment
    • Alleviating Genetic Disease through Gene Therapy
    • Inserting Healthy Genes into the Picture
    • Finding Vehicles to Get Genes to Work
    • Progress on the Gene Therapy Front
    • Utilizing Genetic Information for Precision Medicine
• Part 4: Genetics and Your World
  • Chapter 17: Tracing Human History and the Future of the Planet
    • Genetic Variation Is Everywhere
    • Breaking Down the Hardy-Weinberg Law of Population Genetics
    • Mapping the Gene Pool
    • Changing Forms over Time: The Genetics of Evolution
  • Chapter 18: Solving Mysteries Using DNA
    • Rooting through Your DNA to Find Your Identity
    • Investigating the Scene: Where’s the DNA?
    • Employing DNA to Catch Criminals (And Free the Innocent)
    • It’s All Relative: Finding Family
  • Chapter 19: Genetic Makeovers: Using Genetic Engineering to Change the Genome
    • Genetically Modified Organisms Are Everywhere
    • Old Genes in New Places
    • Looking at the GMO Menagerie
    • Transgenic plants
    • Changing the Blueprint: Gene Editing
  • Chapter 20: Giving Ethical Considerations Their Due
    • Profiling Genetic Discrimination
    • Ordering Up Designer Babies
    • Ethical Issues Surrounding Genetic Testing
    • Informed Consent
    • Patient Autonomy
    • Privacy and Confidentiality
    • Incidental Findings
    • Direct-to-Consumer Testing
    • Practicing Safe Genetic Treatments
    • Genetic Property Rights
• Part 5: The Part of Tens
  • Chapter 21: Ten Defining Events in Genetics
    • The Publication of Darwin’s “The Origin of Species”
    • The Rediscovery of Mendel’s Work
    • DNA Transformation
    • The Discovery of Jumping Genes
    • The Birth of DNA Sequencing
    • The Invention of PCR
    • The Development of Recombinant DNA Technology
    • The Invention of DNA Fingerprinting
    • The Birth of Developmental Genetics
    • The Work of Francis Collins and the Human Genome Project
  • Chapter 22: Ten Hot Issues in Genetics
    • Direct-to-Consumer Genetic Testing
    • Whole Exome Sequencing
    • Whole Genome Sequencing
    • Stem Cell Research
    • The ENCODE Project
    • Proteomics
    • Gene Chips
    • Evolution of Antibiotic Resistance
    • Circumventing Mother Nature
    • Genetics from Afar
• Glossary
• Index
• About the Authors
• Connect with Dummies
• End User License Agreement

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