Berne and Levy Physiology
Höfundar: Koeppen, Bruce M., Stanton, Bruce A.
7.790 kr.
Lýsing:
Pairing necessary detail with concise readability, Berne & Levy Physiology, 8th Edition, provides a perfect balance of content to deliver an in-depth understanding of the body’s dynamic processes. Long respected for its scientifically rigorous approach, this highly regarded, mid-size text offers essential physiology with integrated coverage of biophysics andkey experimental observations and examples—all designed to provide a solid scientific foundation in physiology for future scientists and clinicians.
Uses a logical, organ system-based approach that clearly describes all of the mechanisms that control and regulate bodily function. Includes new clinical case examples, as well as In the Clinic and At the Molecular Level boxes that highlight practical aspects of this fundamental science. Provides key experimental observations and examples that offer a rich understanding of the body's dynamic processes.
Annað
- Höfundar: Bruce M. Koeppen, Bruce A. Stanton
- Útgáfa:8
- Útgáfudagur: 2023-02-12
- Engar takmarkanir á útprentun
- Engar takmarkanir afritun
- Format:ePub
- ISBN 13: 9780323847926
- Print ISBN: 9780323847902
- ISBN 10: 0323847927
Efnisyfirlit
- Cover Image
- Title Page
- Copyright
- Dedication
- Section Authors
- Preface
- Note to Instructors
- Table of Contents
- Section 1 Cellular Physiology
- Chapter 1 Principles of Cell and Membrane Function
- Learning Objectives
- Overview of Eukaryotic Cells
- Vesicular Transport
- Electrochemical Gradient
- Osmosis and Osmotic Pressure
- Key Points
- Chapter 2 Homeostasis: Volume and Composition of Body Fluid Compartments
- Learning Objectives
- Concept of Steady-State Balance
- Volumes and Composition of Body Fluid Compartments
- Maintenance of Cellular Homeostasis
- Principles of Epithelial Transport
- Key Concepts
- Chapter 3 Signal Transduction, Membrane Receptors, Second Messengers, and Regulation of Gene Expression
- Learning Objectives
- Cell-to-Cell Communication
- Receptors
- Receptors and Signal Transduction Pathways
- Regulation of Gene Expression by Signal Transduction Pathways
- Key Points
- Chapter 1 Principles of Cell and Membrane Function
- Chapter 4 The Nervous System: Introduction to Cells and Systems
- Learning Objectives
- Cellular Components of the Nervous System
- The Peripheral Nervous System
- The Central Nervous System
- Nervous Tissue Reactions to Injury
- Key Points
- Chapter 5 Generation and Conduction of Action Potentials
- Learning Objectives
- Membrane Potentials
- Suprathreshold Response: The Action Potential
- Conduction of Action Potentials
- Key Points
- Chapter 6 Synaptic Transmission
- Learning Objectives
- Electrical Synapses
- Chemical Synapses
- Synaptic Integration
- Modulation of Synaptic Activity
- Neurotransmitters
- Neurotransmitter Receptors
- Key Points
- Chapter 7 The Somatosensory System
- Learning Objectives
- Subdivisions of the Somatosensory System
- Discriminatory Touch and Proprioception
- Thalamic and Cortical Somatosensory Areas
- Pain and Temperature Sensation
- Transduction in the Somatosensory System
- Centrifugal Control of Somatosensation
- Key Points
- Chapter 8 The Special Senses
- Learning Objectives
- The Visual System
- The Auditory and Vestibular Systems
- The Chemical Senses
- Key Points
- Chapter 9 Organization of Motor Function
- Learning Objectives
- Principles of Spinal Cord Organization
- Descending Motor Pathways
- Brainstem Control of Posture and Movement
- Motor Control by the Cerebral Cortex
- Motor Control by the Cerebellum
- Motor Control by the Basal Ganglia
- Eye Movement
- Key Points
- Chapter 10 Integrative Functions of the Nervous System
- Learning Objectives
- The Cerebral Cortex
- Key Points
- Chapter 11 The Autonomic Nervous System and Its Central Control
- Learning Objectives
- Organization of the Autonomic Nervous System
- Autonomic Ganglia
- Neurotransmitters
- Central Control of Autonomic Function
- Key Points
- Chapter 12 Skeletal Muscle Physiology
- Learning Objectives
- Skeletal Muscle Physiology
- Organization of Skeletal Muscle
- Control of Skeletal Muscle Activity
- Skeletal Muscle Types
- Modulation of the Force of Contraction
- Modulation of Force by Reflex Arcs
- Skeletal Muscle Tone
- Energy Sources During Contraction
- Oxygen Debt
- Fatigue
- Growth and Development
- Denervation, Reinnervation, and Cross-Innervation
- Response to Exercise
- Delayed-Onset Muscle Soreness
- Biophysical Properties of Skeletal Muscle
- Key Points
- Chapter 13 Cardiac Muscle
- Learning Objectives
- Basic Organization of Cardiac Muscle Cells
- Control of Cardiac Muscle Activity
- Regulation of the Force of Contraction
- Cardiac Muscle Metabolism
- Cardiac Muscle Hypertrophy
- Key Concepts
- Chapter 14 Smooth Muscle
- Learning Objectives
- Overview of Smooth Muscle
- Structure of Smooth Muscle Cells
- Control of Smooth Muscle Activity
- Innervation of Smooth Muscle
- Regulation of Contraction
- Regulation of Myoplasmic Calcium Concentration
- Development and Hypertrophy
- Synthetic and Secretory Functions
- Biophysical Properties of Smooth Muscle
- Key Points
- Chapter 15 Overview of Circulation
- Learning Objectives
- The Heart
- The Cardiovascular Circuit
- Blood Vessels
- Key Points
- Chapter 16 Elements of Cardiac Function
- Learning Objectives
- Overview of Cardiac Function
- Electrical Properties of the Heart
- Normal Sinus Rhythm
- Arrhythmogenic Mechanisms
- Electrocardiography
- Arrhythmias
- The Cardiac Pump
- Key Points
- Chapter 17 Properties of the Vasculature
- Learning Objectives
- Hemodynamics
- The Arterial System
- The Venous System
- Microcirculation and Lymphatic System
- Coronary Circulation
- Cutaneous Circulation
- Skeletal Muscle Circulation
- Cerebral Circulation
- Intestinal Circulation
- Hepatic Circulation
- Fetal Circulation
- Key Points
- Chapter 18 Regulation of the Heart and Vasculature
- Learning Objectives
- Regulation of Heart Rate and Myocardial Performance
- Nervous Control of the Heart Rate
- Regulation of Myocardial Performance
- Regulation of the Peripheral Circulation
- Key Points
- Chapter 19 Integrated Control of the Cardiovascular System
- Learning Objectives
- Regulation of Cardiac Output and Blood Pressure
- Vascular Function Curve
- Relating the Cardiac Function Curve to the Vascular Function Curve
- A More Complete Theoretical Model: The Two-Pump System
- Role of the Heart Rate in Control of Cardiac Output
- Ancillary Factors That Affect the Venous System and Cardiac Output
- Interplay of Central and Peripheral Factors in Control of the Circulation
- Key Points
- Chapter 20 Introduction to the Respiratory System
- Learning Objectives
- Lung Anatomical Structure/Function Relationships
- Circulatory Systems in the Lung
- Innervation
- Lung Embryology, Development, Aging, and Repair
- Key Points
- Chapter 21 Static Lung and Chest Wall Mechanics
- Learning Objectives
- Pressures in the Respiratory System
- How a Pressure Gradient Is Created
- Lung Volumes and Their Measurement
- Lung Volumes and Capacities
- Determinants of Lung Volume
- Pressure-Volume Relationships
- Lung Compliance
- Surface Tension and Surfactant
- Key Points
- Chapter 22 Dynamic Lung and Chest Wall Mechanics
- Learning Objectives
- Dynamic Lung Mechanics
- Work of Breathing
- Key Concepts
- Chapter 23 Ventilation, Perfusion, and Ventilation/Perfusion Relationships
- Learning Objectives
- Ventilation
- Dead Space Ventilation: Anatomical and Physiological
- Alveolar Ventilation
- Pulmonary Vascular Resistance
- Distribution of Pulmonary Blood Flow
- Active Regulation of Blood Flow
- Ventilation/Perfusion Relationships
- Arterial Blood Hypoxemia, Hypoxia, and Hypercarbia
- Low Ventilation/Perfusion
- Alveolar Hypoventilation
- Diffusion Abnormalities
- Mechanisms of Hypercapnia
- Effect of 100% Oxygen on Arterial Blood Gas Abnormalities
- Regional Differences
- Key Points
- Chapter 24 Oxygen and Carbon Dioxide Transport
- Learning Objectives
- Gas Diffusion
- Oxygen Transport
- Carbon Dioxide Transport
- Regulation of Hydrogen Ion Concentration and Acid-Base Balance
- Carbon Dioxide Dissociation Curve
- Key Points
- Chapter 25 Control of Respiration
- Learning Objectives
- Ventilatory Control: An Overview
- Response to Carbon Dioxide
- Control of Ventilation: The Details
- Exercise
- Abnormalities in the Control of Breathing
- Key Points
- Chapter 26 Host Defense and Metabolism in the Lung
- Learning Objectives
- Host Defense
- Epithelial Cells and Commensal Microbiota Protect the Lumen of the Airways
- Clinical Manifestations Associated With Abnormalities in Mucosal Innate and Adaptive Immunity
- Metabolic Functions of the Lung
- Key Points
- Chapter 27 Functional Anatomy and General Principles of Regulation in the Gastrointestinal Tract
- Learning Objectives
- Functional Anatomy
- Regulatory Mechanisms in the Gastrointestinal Tract
- Response of the GI Tract to a Meal
- Key Concepts
- Chapter 28 The Cephalic, Oral, and Esophageal Phases of the Integrated Response to a Meal
- Learning Objectives
- Cephalic and Oral Phases
- Esophageal Phase
- Key Concepts
- Chapter 29 The Gastric Phase of the Integrated Response to a Meal
- Learning Objectives
- Functional Anatomy of the Stomach
- Gastric Secretion
- Digestion in the Stomach
- Gastrointestinal Motility
- Gastric Motility
- Key Concepts
- Chapter 30 The Small Intestinal Phase of the Integrated Response to a Meal
- Learning Objectives
- Gastric Emptying in the Small Intestinal Phase
- Carbohydrate Assimilation
- Protein Assimilation
- Uptake of Peptides and Amino Acids
- Lipid Assimilation
- Water and Electrolyte Secretion and Absorption
- Absorption of Minerals and Water-Soluble Vitamins
- Motor Patterns of the Small Intestine
- Key Concepts
- Chapter 31 The Colonic Phase of the Integrated Response to a Meal
- Learning Objectives
- Overview of the Large Intestine
- Key Concepts
- Chapter 32 Transport and Metabolic Functions of the Liver
- Learning Objectives
- Overview of the Liver and its Functions
- Structural Features of the Liver and Biliary System
- Bile Formation and Secretion
- Ammonia Handling by the Liver
- Clinical Assessment of Liver Function
- Key Concepts
- Chapter 33 Elements of Renal Function
- Learning Objectives
- Overview of Renal Function
- Functional Anatomy of the Kidneys
- Assessment of Renal Function
- Glomerular Filtration
- Renal Blood Flow
- Regulation of Renal Blood Flow and Glomerular Filtration Rate
- Key Points
- Chapter 34 Solute and Water Transport Along the Nephron: Tubular Function
- Learning Objectives
- Solute and Water Reabsorption Along the Nephron
- Regulation of NaCl and Water Reabsorption
- Key Points
- Chapter 35 Control of Body Fluid Osmolality and Volume
- Learning Objectives
- Control of Body Fluid Osmolality: Urine Concentration and Dilution
- Control of Extracellular Fluid Volume and Regulation of Renal NaCl Excretion
- Key Concepts
- Chapter 36 Potassium, Calcium, and Phosphate Homeostasis
- Learning Objectives
- K+ Homeostasis
- Regulation of Plasma [K+]
- Alterations in Plasma [K+]
- K+ Excretion by the Kidneys
- Cellular Mechanism of K+ Transport by Principal and Intercalated Cells in the DT and CCD
- K+ Excretion by the DT and CCD
- Overview of Calcium and Inorganic Phosphate Homeostasis
- Integrative Review of Parathyroid Hormone and Calcitriol on Ca++ and Pi Homeostasis
- Key Concepts
- Chapter 37 Role of the Kidneys in the Regulation of Acid-Base Balance
- Learning Objectives
- The HCO3− Buffer System
- Overview of Acid-Base Balance
- Net Acid Excretion by the Kidneys
- Response to Acid-Base Disorders
- Simple Acid-Base Disorders
- Key Concepts
- Chapter 38 Introduction to the Endocrine System
- Learning Objectives
- Configuration of Feedback Loops Within the Endocrine System
- Chemical Nature of Hormones
- Transport of Hormones in the Circulation
- Cellular Responses to Hormones
- Key Concepts
- Chapter 39 Hormonal Regulation of Energy Metabolism
- Learning Objectives
- Continual Energy Supply and Demand: The Challenge
- Integrated Overview of Energy Metabolism
- Pancreatic Hormones Involved in Metabolic Homeostasis During Different Metabolic Phases
- Hormonal Regulation of Specific Metabolic Reactions and Pathways
- Leptin and Energy Balance
- Key Concepts
- Chapter 40 Hormonal Regulation of Calcium and Phosphate Metabolism
- Learning Objectives
- Crucial Roles of Calcium and Phosphate in Cellular Physiology
- Hormonal Regulation of Calcium and Phosphate: PTH, Vitamin D, and FGF23
- Hormonal Effects on Target Organs
- Regulation of Bone Formation
- Integrated Physiological Regulation of Ca++/Pi Metabolism
- Key Concepts
- Chapter 41 The Hypothalamus and Pituitary Gland
- Learning Objectives
- Anatomy
- The Neurohypophysis
- The Adenohypophysis
- Key Concepts
- Chapter 42 The Thyroid Gland
- Learning Objectives
- Anatomy and Histology of the Thyroid Gland
- Thyroid Hormones
- Transport of Thyroid Hormones
- Cellular Entry and Peripheral Conversion of Thyroid Hormones
- Regulation of Thyroid Function
- Physiological Effects of Thyroid Hormone
- Key Concepts
- Chapter 43 The Adrenal Gland
- Learning Objectives
- Anatomy
- Adrenal Medulla
- Adrenal Cortex
- Key Concepts
- Chapter 44 The Male and Female Reproductive Systems
- Learning Objectives
- The Male Reproductive System
- The Female Reproductive System
- Mammogenesis and Lactation
- Menopause
- Key Concepts
- Acknowledgment
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- Gerð : 208
- Höfundur : Stanton, Bruce A. , Bruce A. Stanton , Bruce Koeppen, Bruce Stanton , Bruce M. Koeppen , Koeppen, Bruce M.
- Útgáfuár : 2009
- Leyfi : 380
