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Fenner and White's Medical Virology

Vörunúmer: 9780123751577
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Fenner and White's Medical Virology

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Rafbók til leigu í 30 daga. Útgáfa: 5
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Efnisyfirlit

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Dedication
  • Foreword
  • Preface
  • Part I: Principles of Virology
    • Chapter 1. History and Impact of Virology
      • Abstract
      • Why Study Virology?
      • A Brief History of Virology
      • The Virosphere
      • The Nature of Viruses
      • Scope of This Book
      • Further Reading
    • Chapter 2. Classification of Viruses and Phylogenetic Relationships
      • Abstract
      • Viral Taxonomy
      • Viral Nomenclature
      • Groupings of Viruses on the Basis of Epidemiological Criteria
      • Taxonomy and the Causal Relationship between Virus and Disease
      • Genome Sequencing and Virus Evolution
      • Further Reading
    • Chapter 3. Virion Structure and Composition
      • Abstract
      • Physical Methods for Studying Virus Structure
      • Chemical Composition of Virions
      • Virion Symmetry
      • Further Reading
    • Chapter 4. Virus Replication
      • Abstract
      • Growth of Viruses
      • The Virus Replication Cycle
      • Satellite Viruses and Viroids
      • Generation of Genetic Diversity
      • Quantitative Virus Assays
      • Defective Interfering Viruses
      • Further Reading
    • Chapter 5. Innate Immunity
      • Abstract
      • Innate Responses
      • Monocytes, Macrophages, and Dendritic Cells
      • The Role of Natural Killer (NK) Cells and the Link with Adaptive Immunity
      • The Importance of Molecular Recognition
      • Interferons
      • Cell Death and Apoptosis
      • Evasion Strategies
      • Further Reading
    • Chapter 6. Adaptive Immune Responses to Infection
      • Abstract
      • Overview of the Adaptive Immune Responses to Viral Infection
      • The Major Histocompatibility Complex (MHC) and Antigen Presentation
      • Antibodies
      • Cytokines
      • Recovery from Viral Infection
      • Neutralization of Viral Infectivity by Antibodies
      • Immunity to Reinfection
      • Immunological Memory
      • Further Reading
    • Chapter 7. Pathogenesis of Virus Infections
      • Abstract
      • The Incoming Virus Inoculum
      • Routes of Entry—A Major Factor Governing the Specific Pattern of Infection
      • Mechanisms of Virus Spread Within the Body
      • Virus Infection of Target Organs
      • Persistent Virus Infections—Mechanisms Influencing Persistence
      • Mechanisms of Disease Production
      • Viruses and Immunosuppression
      • Viral Virulence and Host Resistance to Infection
      • Co-infections
      • Further Reading
    • Chapter 8. Patterns of Infection
      • Abstract
      • Transient Localized Infections
      • Transient Systemic Infections
      • Persistent Infections
      • Persistent Localized Infections
      • Persistent Systemic Infections
      • Further Reading
    • Chapter 9. Mechanisms of Viral Oncogenesis
      • Abstract
      • Definitions and Overview of Virus Transformation
      • Oncogenes and Tumor Suppressor Genes
      • Oncogenesis by Retroviruses
      • Oncogenesis by Small DNA Viruses
      • Oncogenesis by Large DNA Viruses
      • Other Important Viruses Associated with Cancers
      • The Prevention and Management of Virally Induced Tumors
      • Further Reading
    • Chapter 10. Laboratory Diagnosis of Virus Diseases
      • Abstract
      • Rationale for Performing Laboratory Virus Diagnosis
      • Collection, Packaging, and Transport of Samples
      • Direct Identification of Virus, Viral Antigen, or Viral Genome
      • Virus Isolation
      • Measurement of Serum Antibodies
      • Interpretation of Laboratory Results
      • Laboratory Safety
      • Further Reading
    • Chapter 11. Vaccines and Vaccination
      • Abstract
      • Vaccine Design and Production
      • Vaccine Safety, Efficacy, and Practical Usage
      • Factors Affecting Vaccine Safety
      • Passive Protection
      • Vaccination Policy and Programs
      • Further Reading
    • Chapter 12. Antiviral Chemotherapy
      • Abstract
      • Strategies for the Development of AntiViral Agents
      • Clinical Application
      • Clinical Strategies
      • Mechanisms of Action and Role of Individual AntiViral Drugs
      • Newer Approaches Under Development
      • Further Reading
    • Chapter 13. Epidemiology of Viral Infections
      • Abstract
      • Mechanisms of Virus Survival
      • Viral Shedding and Routes of Transmission
      • Factors Affecting the Dynamics of Viral Infections
      • Epidemiological Investigations
      • Mathematical Modeling
      • Further Reading
    • Chapter 14. Control, Prevention, and Eradication
      • Abstract
      • Surveillance and Modeling of Virus Diseases
      • Measures to Minimize Transmission
      • Immunization
      • Eradication
      • Bioterrorism
      • Further Reading
    • Chapter 15. Emerging Virus Diseases
      • Abstract
      • Increased Recognition and Changes in Disease Patterns
      • Factors Affecting Emergence
      • Climate Change
      • Ease of Travel
      • Animals as a Source of Human Diseases
      • Prevention and Control
      • Further Reading
  • Part II: Specific Virus Diseases of Humans
    • Chapter 16. Poxviruses
      • Abstract
      • Properties of Poxviruses
      • Diseases Caused by Members of the Genus Orthopoxvirus
      • Diseases Caused by Members of the Genus Molluscipoxvirus
      • Diseases Caused by Members of the Genus Yatapoxvirus
      • Diseases Caused by Members of the Genus Parapoxvirus
      • Further Reading
    • Chapter 17. Herpesviruses
      • Abstract
      • Properties of the Viruses
      • Herpes Simplex Virus Infection
      • Varicella-Zoster Virus Infection
      • Cytomegalovirus Infection
      • Human Herpesviruses 6 and 7 (HHV-6 and HHV-7) Infection
      • Epstein-Barr Virus Infection
      • Human Herpesvirus 8 (HHV-8: Kaposi’s Sarcoma-Associated Herpesvirus) Infection
      • B Virus (Macacine Herpesvirus 1) Infection
      • Further Reading
    • Chapter 18. Adenoviruses
      • Abstract
      • Classification
      • Properties of Adenoviruses
      • Virus Replication
      • Adenovirus Diseases
      • Pathogenesis, Pathology, and Immunity
      • Laboratory Diagnosis
      • Epidemiology, Prevention, Control, Treatment
      • Adenoviruses as Vectors for the Delivery of Heterologous DNA
      • Further Reading
    • Chapter 19. Papillomaviruses
      • Abstract
      • Classification
      • Properties of Papillomaviruses
      • Viral Replication
      • Clinical Features
      • Pathogenesis and Immunity
      • Natural History of Genital HPV Infection
      • Laboratory Diagnosis
      • Epidemiology
      • Treatment and Prevention
      • Further Reading
    • Chapter 20. Polyomaviruses
      • Abstract
      • Classification, Properties, and Replication
      • Pathogenesis
      • BK Polyomavirus
      • JC Polyomavirus
      • Other Recently Described Human Polyomaviruses
      • Further Reading
    • Chapter 21. Parvoviruses
      • Abstract
      • Classification
      • Properties of Parvoviridae
      • Viral Replication
      • Parvovirus B19
      • Pathogenesis and Immunity
      • Clinical Features
      • Transient Aplastic Crisis
      • Other Complications of Parvovirus B19 Infection
      • Laboratory Diagnosis
      • Epidemiology
      • Treatment and Control
      • Dependoviruses
      • Human Bocaviruses
      • Further Reading
    • Chapter 22. Hepatitis B and Hepatitis Delta Viruses
      • Abstract
      • Hepatitis B Virus
      • Hepatitis Delta Virus
      • Classification
      • Virion Properties
      • Viral Replication
      • Clinical Features
      • Pathogenesis
      • Laboratory Diagnosis
      • Epidemiology
      • Treatment and Prevention
      • Further Reading
    • Chapter 23. Retroviruses
      • Abstract
      • Properties of Retroviridae
      • Viral Replication
      • Human T cell Lymphotropic Viruses
      • Human Immunodeficiency Viruses
      • Subfamily Spumavirinae
      • Further Reading
    • Chapter 24. Reoviruses
      • Abstract
      • Properties of Reoviruses
      • Viral Replication
      • Rotavirus Gastroenteritis
      • Orbiviruses
      • Coltiviruses
      • Orthoreoviruses
      • Further Reading
    • Chapter 25. Orthomyxoviruses
      • Abstract
      • Properties of Orthomyxoviruses
      • Influenza
      • Further Reading
    • Chapter 26. Paramyxoviruses
      • Abstract
      • Properties of Paramyxoviruses
      • Respiratory Syncytial Virus Infection
      • Parainfluenza Virus Infections
      • Human Metapneumovirus Infection
      • Measles
      • Mumps
      • Henipavirus Infections
      • Further Reading
    • Chapter 27. Rhabdoviruses
      • Abstract
      • Properties of Rhabdoviruses
      • Rabies
      • Vesicular Stomatitis and Other Rhabdoviruses
      • Further Reading
    • Chapter 28. Filoviruses
      • Abstract
      • Properties of Filoviruses
      • Ebola and Marburg Virus Disease (Ebola and Marburg Hemorrhagic Fever)
      • Further Reading
    • Chapter 29. Bunyaviruses
      • Abstract
      • Properties of Bunyaviruses
      • Diseases Caused by Members of the Genus Orthobunyavirus
      • Diseases Caused by Members of the Genus Phlebovirus
      • Diseases Caused by Members of the Genus Nairovirus
      • Diseases Caused by Members of the Genus Hantavirus
      • Further Reading
    • Chapter 30. Arenaviruses
      • Abstract
      • Properties of Arenaviruses
      • Lymphocytic Choriomeningitis Virus Infection
      • Lassa Fever
      • Lujo Virus Infection
      • South American Hemorrhagic Fevers
      • Further Reading
    • Chapter 31. Coronaviruses
      • Abstract
      • Properties of Coronaviruses
      • Human Coronavirus Infections
      • Severe Acute Respiratory Virus (SARS-CoV)
      • Middle East Respiratory Virus (MERS-CoV)
      • Further Reading
    • Chapter 32. Picornaviruses
      • Abstract
      • Properties of Picornaviruses
      • Poliomyelitis
      • Enteroviruses A, B, C, D, and Parechoviruses
      • Human Rhinoviruses A, B, and C
      • Hepatitis A (HAV)
      • Further Reading
    • Chapter 33. Caliciviruses
      • Abstract
      • Classification
      • Virion Properties
      • Calicivirus (Norovirus and Sapovirus) Gastroenteritis
      • Further Reading
    • Chapter 34. Astroviruses
      • Abstract
      • Properties of Astroviruses
      • Clinical Features
      • Laboratory Diagnosis
      • Epidemiology
      • Prevention
      • Further Reading
    • Chapter 35. Togaviruses
      • Abstract
      • Properties of Togaviruses
      • Diseases Caused by Members of the Genus Alphavirus
      • Alphaviruses Causing Encephalitis—Eastern, Western, and Venezuelan Encephalitis
      • Alphavirus Infections Marked by Fever, Rash, Myalgia, Arthralgia, and Arthritis
      • Chikungunya
      • Other Alphavirus Infections
      • Disease Caused by the Rubivirus Rubella Virus
      • Further Reading
    • Chapter 36. Flaviviruses
      • Abstract
      • Properties of Flaviviruses
      • Diseases Caused by Mosquito-Borne Member Viruses of the Genus Flavivirus
      • Yellow Fever
      • Dengue
      • Zika Virus
      • Japanese Encephalitis
      • West Nile Virus Infection
      • St. Louis Encephalitis
      • Usutu Virus Infection
      • Murray Valley (Australian) Encephalitis
      • Rocio Virus Encephalitis
      • Diseases Caused by Tick-Borne Members of the Genus Flavivirus
      • Diseases Caused by Members of the Genus Hepacivirus
      • Other Hepaciviruses
      • Further Reading
    • Chapter 37. Hepeviruses
      • Abstract
      • Classification and Properties of Hepatitis E Virus
      • Viral Replication
      • Clinical Features
      • Pathology, Pathogenesis, and Immunity
      • Laboratory Diagnosis
      • Epidemiology, Prevention, Control, and Therapeutics
      • Further Reading
    • Chapter 38. Prions
      • Abstract
      • Properties of Prions
      • Human Prion Diseases
      • Diagnosis
      • Treatment and Prevention
      • Other Chronic Neurodegenerative Diseases
      • Further Reading
    • Chapter 39. Viral Syndromes
      • Abstract
      • The Human Virome
      • Viral Diseases of the Respiratory Tract
      • Viral Gastroenteritis
      • Viral Diseases of the Central Nervous System
      • Viral Skin Rashes
      • Viral Hemorrhagic Fevers
      • Viral Genitourinary Infections
      • Viral Diseases of the Eye
      • Viral Arthritis
      • Viral Carditis
      • Viral Hepatitis
      • Viral Pancreatitis and Diabetes
      • Chronic Fatigue Syndrome
      • Congenital and Perinatal Viral Infections
      • Viral Infections in Immunocompromised Patients
      • Diseases of Unknown Etiology
      • Further Reading
  • Index

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Vörunúmer: 9780123751577
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