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Medical Pharmacology and Therapeutics E-Book

Vörumerki: Elsevier
Vörunúmer: 9780702071904
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Medical Pharmacology and Therapeutics E-Book

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Rafbók til eignar. Rafbók til eignar þarf að hlaða niður á þau tæki sem þú vilt nota innan eins árs frá því bókin er keypt. Útgáfa: 5
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Efnisyfirlit

  • Instructions for online access
  • Cover image
  • Title Page
  • Table of Contents
  • Dedication
  • Copyright
  • Preface
  • Drug dosage and nomenclature
    • Drug Nomenclature
    • Drug Dosages
  • Section 1 General Principles
    • 1 Principles of pharmacology and mechanisms of drug action
      • Studying Pharmacology
      • Receptors and Receptor-Mediated Mechanisms
      • Properties of Drug Action
      • Types of Drug Action
      • Tolerance to Drug Effects
      • Genetic Variation in Drug Responses
      • Summary
      • Self-Assessment
      • Answers
      • Further Reading
    • 2 Pharmacokinetics
      • The Biological Basis of Pharmacokinetics
      • Absorption
      • Distribution
      • Elimination
      • The Mathematical Basis of Pharmacokinetics
      • Absorption
      • Distribution
      • Elimination
      • Chronic Administration
      • Pharmacokinetics of Biological Drugs
      • Genetic Variation and Pharmacokinetics
      • Self-Assessment
      • Answers
      • Further Reading
    • 3 Drug discovery, safety and efficacy
      • Drug Discovery
      • Drug Approval
      • Establishing Safety and Efficacy
      • Self-Assessment
      • Answers
      • Further Reading
    • 4 Neurotransmission and the peripheral autonomic nervous system
      • The Central and Peripheral Nervous Systems
      • Principles of Neurotransmission
      • The Peripheral Autonomic Nervous System
      • The Sympathetic Nervous System and Noradrenergic Transmission
      • The Parasympathetic Nervous System and Cholinergic Transmission
      • Other Transmitters in the Peripheral Nervous System
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 2 The Cardiovascular System
    • 5 Ischaemic heart disease
      • Myocardial Perfusion
      • Clinical Manifestations of Myocardial Ischaemia
      • Drugs for Treating Angina
      • Management of Stable Angina
      • Management of Acute Coronary Syndromes
      • Self-Assessment
      • Answers
      • Further Reading
    • 6 Systemic and pulmonary hypertension
      • Systemic Hypertension
      • Pulmonary Arterial Hypertension
      • Self-Assessment
      • Answers
      • Further Reading
    • 7 Heart failure
      • Maintenance of Cardiac Output
      • Pathophysiology of Heart Failure
      • Positive Inotropic Drugs for the Treatment of Heart Failure
      • Management of Heart Failure
      • Self-Assessment
      • Answers
      • Further Reading
    • 8 Cardiac arrhythmias
      • Basic Cardiac Electrophysiology
      • Mechanisms of Arrhythmogenesis
      • Mechanisms of Action and Classification of Antiarrhythmic Drugs
      • Drug Treatment of Arrhythmias
      • Self-Assessment
      • Answers
      • Further Reading
    • 9 Cerebrovascular disease and dementia
      • Stroke
      • Subarachnoid Haemorrhage
      • Dementia
      • Self-Assessment
      • Answers
      • Further Reading
    • 10 Peripheral vascular disease
      • Atheromatous Peripheral Vascular Disease
      • Acute and Critical Limb Ischaemia
      • Raynaud's Phenomenon
      • Self-Assessment
      • Answers
      • Further Reading
    • 11 Haemostasis
      • Platelets and Platelet Aggregation
      • Blood Coagulation and the Coagulation Cascade
      • Antiplatelet Drugs
      • Clinical Uses of Antiplatelet Drugs
      • Anticoagulant Drugs
      • Clinical Uses of Anticoagulants
      • The Fibrinolytic System
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 3 The Respiratory System
    • 12 Asthma and chronic obstructive pulmonary disease
      • Asthma
      • Chronic Obstructive Pulmonary Disease
      • Drugs for Asthma and Chronic Obstructive Pulmonary Disease
      • Management of Asthma
      • Management of Chronic Obstructive Pulmonary Disease
      • Self-Assessment
      • Answers
      • Further Reading
    • 13 Respiratory disorders
      • Cough
      • Respiratory Stimulants (Analeptic Drugs)
      • Cystic Fibrosis
      • Idiopathic Pulmonary Fibrosis
      • Neonatal Respiratory Distress Syndrome
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 4 The Renal System
    • 14 Diuretics
      • Functions of the Kidney
      • Diuretic Drugs
      • Self-Assessment
      • Answers
      • Further Reading
    • 15 Disorders of micturition
      • Pathophysiology of Micturition
      • Overactive Bladder Syndrome
      • Hypotonic Bladder
      • Urethral Sphincter Incompetence
      • Lower Urinary Tract Symptoms in Men and Benign Prostatic Hypertrophy
      • Self-Assessment
      • Answers
      • Further Reading
    • 16 Erectile dysfunction
      • Physiology of Erection
      • Drugs for Erectile Dysfunction
      • Management of Erectile Dysfunction
      • Premature Ejaculation
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 5 The Nervous System
    • 17 General anaesthetics
      • Mechanisms of Action of General Anaesthetics
      • Drugs Used in Anaesthesia
      • Self-Assessment
      • Answers
      • Further Reading
    • 18 Local anaesthetics
      • Pharmacology
      • Techniques of Administration
      • Self-Assessment
      • Answers
      • Further Reading
    • 19 Opioid analgesics and the management of pain
      • Pain and Pain Perception
      • Analgesic Drugs
      • Pain Management
      • Self-Assessment
      • Answers
      • Further Reading
    • 20 Anxiety, obsessive-compulsive disorder and insomnia
      • Anxiety Disorders
      • Obsessive-Compulsive Disorder
      • Insomnia
      • Self-Assessment
      • Answers
      • Further Reading
    • 21 Schizophrenia and bipolar disorder
      • Schizophrenia
      • Antipsychotic Drugs
      • Mania and Bipolar Disorder
      • Mood-Stabilising Drugs for Bipolar Disorder
      • Management of Bipolar Disorder
      • Self-Assessment
      • AnswerS
      • Further Reading
    • 22 Depression, attention deficit hyperactivity disorder and narcolepsy
      • Depression
      • Attention Deficit Hyperactivity Disorder and Narcolepsy
      • Self-Assessment
      • Answers
      • Further Reading
    • 23 Epilepsy
      • Pathological Basis of Epilepsy
      • Antiepileptic Drugs
      • Management of Epilepsy
      • Self-Assessment
      • Answers
      • Further Reading
    • 24 Extrapyramidal movement disorders and spasticity
      • The Basal Ganglia and Control of Motor Function
      • Parkinson's Disease and Related Syndromes
      • Drugs for Parkinson's Disease
      • Management of Parkinson's Disease and Related Syndromes
      • Other Involuntary Movement Disorders (Dyskinesias)
      • Management of Dyskinesias and Dystonias
      • Spasticity
      • Management of Spasticity
      • Self-Assessment
      • Answers
      • Further Reading
    • 25 Other neurological disorders
      • Multiple Sclerosis
      • Motor Neuron Disease
      • Guillain–Barré Syndrome
      • Self-Assessment
      • Answers
      • Further Reading
    • 26 Migraine and other headaches
      • Migraine
      • Pathogenesis of Migraine
      • Drugs for Migraine
      • Management of Migraine and Other Headaches
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 6 The Musculoskeletal System
    • 27 The neuromuscular junction and neuromuscular blockade
      • Neuromuscular Transmission
      • Drugs Acting at the Neuromuscular Junction
      • Indications for Neuromuscular-Blocking Drugs
      • Antagonising Neuromuscular Block
      • Self-Assessment
      • Answers
      • Further Reading
    • 28 Myasthenia gravis
      • Acetylcholinesterase Inhibitors
      • Management of Myasthenia Gravis
      • Lambert–Eaton Myasthenic Syndrome
      • Self-Assessment
      • Answers
      • Further Reading
    • 29 Nonsteroidal antiinflammatory drugs
      • The Role of Cyclo-Oxygenase Enzymes in the Actions of Nonsteroidal AntiInflammatory Drugs
      • Nonsteroidal AntiInflammatory Drugs
      • Self-Assessment
      • Answers
      • Further Reading
    • 30 Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis
      • Rheumatoid Arthritis
      • Other Types of Inflammatory Arthritis: the Spondyloarthritides
      • Conventional Disease-Modifying Antirheumatic Drugs
      • Biological Drugs for Inflammatory Arthritis
      • Management of Rheumatoid Arthritis
      • Management of Spondyloarthritides
      • Osteoarthritis
      • Self-Assessment
      • Answers
      • Further Reading
    • 31 Hyperuricaemia and gout
      • The Pathophysiology of Gout
      • Drugs for the Treatment of Gout and Prevention of Hyperuricaemia
      • Treatment of Gout
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 7 The Gastrointestinal System
    • 32 Nausea and vomiting
      • Nausea and Vomiting
      • Vertigo
      • Self-Assessment
      • Answers
      • Further Reading
    • 33 Dyspepsia and peptic ulcer disease
      • The Spectrum of Disease
      • Drugs for Treating Dyspepsia, Peptic Ulcer and Gastro-Oesophageal Reflux Disease
      • Management of Dyspepsia, Peptic Ulcer and Gastro-Oesophageal Reflux Disease
      • Self-Assessment
      • Answers
      • Further Reading
    • 34 Inflammatory bowel disease
      • Drugs for Inflammatory Bowel Disease
      • Management of Inflammatory Bowel Disease
      • Self-Assessment
      • Answers
      • Further Reading
    • 35 Constipation, diarrhoea and irritable bowel syndrome
      • Constipation
      • Diarrhoea
      • Irritable Bowel Syndrome
      • Self-Assessment
      • Answers
      • Further Reading
    • 36 Liver disease
      • Acute Liver Failure
      • Chronic Liver Disease and Liver Cirrhosis
      • Autoimmune Hepatitis
      • Primary Biliary Cirrhosis
      • Chronic Viral Hepatitis
      • Complications of Cirrhosis
      • Self-Assessment
      • Answers
      • Further Reading
    • 37 Obesity
      • Pathogenesis of Obesity
      • Drugs for Treatment of Obesity
      • Management of Obesity
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 8 The Immune System
    • 38 The immune response and immunosuppressant drugs
      • Biological Basis of the Immune Response
      • Immunosuppressant Drugs
      • Immunosuppression in Inflammatory and Autoimmune Disease
      • Immunosuppression in Organ Transplantation
      • Long-Term Effects of Immunosuppression
      • Self-Assessment
      • Answers
      • Further Reading
    • 39 Antihistamines and allergic disease
      • Atopy, Allergic Disorders and Anaphylaxis
      • Histamine as an Autacoid in Host Defence
      • Histamine H1 Receptor Antagonists (Antihistamines)
      • Management of Allergic Disorders
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 9 The Endocrine System and Metabolism
    • 40 Diabetes mellitus
      • Control of Blood Glucose
      • Diabetes Mellitus
      • Insulin and Insulin Analogues for Treatment of Diabetes Mellitus
      • Other Parenteral Glucose-Lowering Drugs
      • Oral Glucose-Lowering Drugs
      • Drugs to Increase Plasma Glucose Levels
      • Management of Type 1 Diabetes Mellitus
      • Management of Type 2 Diabetes Mellitus
      • Self-Assessment
      • Answers
      • Further Reading
    • 41 The thyroid and control of metabolic rate
      • Thyroid Function
      • Hyperthyroidism
      • Hypothyroidism
      • Self-Assessment
      • Answers
      • Further Reading
    • 42 Calcium metabolism and metabolic bone disease
      • Physiology of Bone Turnover
      • Hypercalcaemia
      • Hypocalcaemia
      • Metabolic Bone Disease
      • Self-Assessment
      • Answers
      • Further Reading
    • 43 Pituitary and hypothalamic hormones
      • Anterior Pituitary and Related Hypothalamic Hormones
      • Posterior Pituitary Hormones
      • Hypopituitarism
      • Self-Assessment
      • Answers
      • Further Reading
    • 44 Corticosteroids (glucocorticoids and mineralocorticoids)
      • Corticosteroid Hormones
      • Glucocorticoids
      • Mineralocorticoids
      • Self-Assessment
      • Answers
      • Further Reading
    • 45 Female reproduction
      • Physiology of the Menstrual Cycle
      • Physiology of Pregnancy
      • Steroidal Contraceptives
      • Hormone-Replacement Therapy
      • Pregnancy and Labour
      • Self-Assessment
      • Answers
      • Further Reading
    • 46 Androgens, antiandrogens and anabolic steroids
      • Androgens and Anabolic Steroids
      • Anabolic Steroids
      • AntiAndrogens
      • 5a-Reductase Inhibitors
      • Self-Assessment
      • Answers
      • Further Reading
    • 47 Anaemia and haematopoietic colony-stimulating factors
      • Anaemia
      • Neutropenia
      • Self-Assessment
      • Answers
      • Further Reading
    • 48 Lipid disorders
      • Lipids and Lipoproteins
      • Formation of Atheroma
      • Drugs for Hyperlipidaemias
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 10 The Skin and Eyes
    • 49 Skin disorders
      • Vehicles for Topical Skin Applications
      • Atopic and Contact Dermatitis
      • Psoriasis
      • Acne Vulgaris
      • Self-Assessment
      • Answers
      • Further Reading
    • 50 The eye
      • Topical Application of Drugs to the Eye
      • Glaucoma
      • Mydriatic and Cycloplegic Drugs
      • Other Topical Applications for the Eye
      • Dry Eye Syndrome
      • Age-Related Macular Degeneration
      • Diabetic Retinopathy
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 11 Chemotherapy
    • 51 Chemotherapy of infections
      • Bacterial Infections
      • Fungal Infections
      • Viral Infections
      • Protozoal Infections
      • Helminthic Infections
      • Self-Assessment
      • Answers
      • Further Reading
    • 52 Chemotherapy of malignancy
      • Molecular Origins of Cancer
      • Antineoplastic Drugs
      • Specific Antineoplastic Drugs
      • Clinical Uses of Antineoplastic Drugs
      • AntiCancer Drug Therapy for Specific Malignancies
      • Self-Assessment
      • Answers
      • Further Reading
  • Section 12 General Features: Drug Toxicity and Prescribing
    • 53 Drug toxicity and overdose
      • Drug Toxicity and Adverse Effects
      • Self-Poisoning and Drug Overdose
      • Some Common Specific Poisonings
      • Self-Assessment
      • Answers
      • Further Reading
    • 54 Substance abuse and dependence
      • The Biological Basis of Dependence
      • Drugs of Abuse
      • Controlled Drugs
      • Self-Assessment
      • Answers
      • Further Reading
    • 55 Prescribing, adherence and information about medicines
      • Duties of the Prescriber
      • Adherence, Concordance and Compliance
      • Rational Prescribing
      • Prescribing Safety Assessment
      • Further Reading
    • 56 Drug therapy in special situations
      • Prescribing in Pregnancy
      • Drugs and Breastfeeding
      • Prescribing for Children
      • Prescribing for Older People
      • Prescribing in Renal Failure
      • Prescribing in Liver Disease
      • Prescribing in Palliative Care
      • Drug Interactions
      • Self-Assessment
      • Answers
      • Further Reading
  • Index

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Vörumerki: Elsevier
Vörunúmer: 9780702071904
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