Annað
- Höfundur: Ricki Lewis
- Útgáfa:14
- Útgáfudagur: 2023-09-05
- Hægt að prenta út 2 bls.
- Hægt að afrita 2 bls.
- Format:ePub
- ISBN 13: 9781266450006
- Print ISBN: 9781266283192
- ISBN 10: 1266450009
Efnisyfirlit
- Table of Contents and Preface
- Cover Page
- Title Page
- Copyright Page
- About the Author
- Dedication
- Brief Contents
- Contents
- Preface
- A Reawakening of Interest in Genetics as the Field Broadens and Deepens
- What Sets This Book Apart
- New to This Edition
- Acknowledgments
- Applying Human Genetics
- The Human Touch
- The Lewis Guided Learning System
- Dynamic Art Program
- Connect Remote Proctoring & Browser-Locking Capabilities
- Connect
- Instructors The Power of Connections
- Students Get Learning that Fits You
- Chapter 1 Introduction
- The Information in a Human Genome
- 1.1 Introducing Genes and Genomes
- 1.2 Levels of Genetics and Genomics
- Instructions and Information: DNA
- The Body: Cells, Tissues, and Organs
- Relationships: From Individuals to Families
- The Bigger Picture: From Populations to Evolution
- 1.3 Applications of Genetics and Genomics
- Establishing Identity
- Illuminating History
- Biobanks
- Precision Medicine
- Genetic Modification
- Exome and Genome Sequencing
- 1.4 A Global Perspective on Genomes
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Forensics Focus
- Case Studies and Research Results
- Chapter 2 Introduction
- 2.1 Introducing Cells
- 2.2 Cell Components
- Chemical Constituents
- Organelles
- Biological Membranes
- The Cytoskeleton
- 2.3 Cell Division and Death
- The Cell Cycle
- Apoptosis
- 2.4 Stem Cells
- Cell Lineages
- Stem Cell Sources
- Stem Cell Applications
- 2.5 The Human Microbiome
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Forensics Focus
- Case Studies and Research Results
- Chapter 3 Introduction
- 3.1 The Reproductive System
- The Male
- The Female
- 3.2 Meiosis
- 3.3 Gametes Mature
- Sperm Form
- Oocytes Form
- Meiosis and Mutations
- 3.4 Prenatal Development
- Sperm and Oocyte Meet at Fertilization
- The Embryo Cleaves and Implants
- The Embryo Forms
- Supportive Structures Form
- Multiples
- The Embryo Develops
- The Fetus Grows
- 3.5 Congenital Disorders
- The Critical Period
- Teratogens
- 3.6 Maturation and Aging
- Adult-Onset Inherited Diseases
- Syndromes That Resemble Accelerated Aging
- Genes and Longevity
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 4 Introduction
- Single-Gene Inheritance
- 4.1 Following the Inheritance of One Gene
- Characteristics of Single-Gene Diseases
- Mendel’s Experiments
- Terms and Tools to Follow Segregating Genes
- 4.2 Single-Gene Inheritance Is Rare
- Eye Color
- Modes of Inheritance
- Solving a Problem in Following a Single Gene
- On the Meaning of Dominance and Recessiveness
- 4.3 Following the Inheritance of More Than One Gene
- Mendel’s Second Law
- Solving a Problem in Following Multiple Genes
- 4.4 Pedigree Analysis
- Pedigrees Then and Now
- Pedigrees Display Mendel’s Laws
- Solving a Problem in Conditional Probability
- Exome and Genome Sequencing Clarify Pedigrees
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Forensics Focus
- Case Studies and Research Results
- Chapter 5 Introduction
- 5.1 When Gene Expression Appears to Alter Mendelian Ratios
- Lethal Allele Combinations
- Multiple Alleles
- Different Dominance Relationships
- Epistasis
- Penetrance and Expressivity
- Pleiotropy
- Genetic Heterogeneity
- Phenocopies
- The Human Genome Sequence Adds Perspective
- 5.2 Mitochondrial Genes
- Mitochondrial Diseases
- Heteroplasmy
- Mitochondrial DNA Reveals the Past
- 5.3 Linkage
- Discovery in Pea Plants
- Linkage Maps
- Solving Linkage Problems Uses Logic
- From Linkage to Genome-Wide Associations
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Forensics Focus
- Case Studies and Research Results
- Chapter 6 Introduction
- 6.1 Our Sexual Selves
- Sexual Development
- Sex Chromosomes
- The Phenotype Forms
- Is Same-Sex Attraction Inherited?
- Sex Ratio
- 6.2 Traits Inherited on Sex Chromosomes
- X-Linked Recessive Inheritance
- X-Linked Dominant Inheritance
- Solving a Problem of X-Linked Inheritance
- Solution
- 6.3 Sex-Limited and Sex-Influenced Traits
- Sex-Limited Traits
- Sex-Influenced Traits
- 6.4 X Inactivation
- Equaling Out the Sexes
- Effect of X Inactivation on the Phenotype
- X Inactivation and COVID-19 Severity
- 6.5 Parent-of-Origin Effects
- Genomic Imprinting
- Imprinting Diseases in Humans
- Different Timetables in Sperm and Oocyte Formation
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 7 Introduction
- 7.1 Genes and the Environment Mold Traits
- 7.2 Polygenic Traits Are Continuously Varying
- Fingerprint Patterns
- Height
- Skin Color and Race
- 7.3 Methods to Investigate Complex Traits
- Empiric Risk
- Heritability
- Adopted Individuals
- Twins
- Genome-Wide Association Studies
- 7.4 A Closer Look: Body Weight
- Genes That Affect Weight
- Environmental Influences on Weight
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 8 Introduction
- 8.1 Genes and Behavior
- 8.2 Sleep
- Narcolepsy
- Familial Advanced Sleep Phase Syndrome
- 8.3 Intelligence and Intellectual Disability
- 8.4 Drug Addiction
- Substance Use Disorders
- Addictive Drugs
- 8.5 Mood Disorders
- Major Depressive Disorder
- Bipolar Disorder
- 8.6 Schizophrenia
- Signs and Symptoms
- A Disorder of Synaptic Pruning
- 8.7 Autism
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Forensics Focus
- Case Studies and Research Results
- Chapter 9 Introduction
- DNA Structure and Replication
- 9.1 Experiments Identify and Describe the Genetic Material
- DNA Is the Hereditary Molecule
- Protein Is Not the Hereditary Molecule
- Discovering the Structure of DNA
- 9.2 DNA Structure
- Nucleotide Building Blocks
- Polynucleotide Chains Are Antiparallel
- Complementary Base Pairing
- DNA Configuration in the Nucleus
- 9.3 DNA Replication—Maintaining Genetic Information
- DNA Replication Is Semiconservative
- Steps of DNA Replication
- Polymerase Chain Reaction
- 9.4 Sequencing DNA
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 10 Introduction
- 10.1 The Importance of Proteins
- 10.2 Transcription Copies the Information in DNA into RNA
- RNA Structure and Types
- Transcription Factors
- Steps of Transcription
- RNA Processing
- 10.3 Translation of a Protein
- The Genetic Code
- Building a Protein
- 10.4 Processing a Protein
- Protein Folding and Misfolding
- Diseases of Protein Misfolding
- Prion Diseases
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 11 Introduction
- 11.1 Gene Expression Through Time and Tissue
- Inside a COVID-Ravaged Lung
- Globin Chain Switching
- Building Tissues and Organs
- Shared Gene Expression Connects Diseases
- Proteomics
- 11.2 Control of Gene Expression
- Chromatin Remodeling
- MicroRNAs
- Microproteins
- 11.3 Maximizing Genetic Information
- Alternative Splicing
- Exons and Introns in Different Contexts
- Post-translational Modification
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Forensics Focus
- Case Studies and Research Results
- Chapter 12 Introduction
- 12.1 The Nature of Gene Variants
- Terminology
- Germline and Somatic Mutation
- A Closer Look at Two Mutations
- 12.2 Allelic Diseases
- 12.3 Causes of Mutation
- Spontaneous Mutation
- Induced Mutation
- Accidental Exposures to Mutagens
- Natural Exposure to Mutagens
- 12.4 Types of Mutations
- Point Mutations
- Splice-Site Mutations
- Deletions and Insertions
- Pseudogenes and Transposons
- Expanding Repeats
- Copy Number Variants
- 12.5 The Importance of Position
- Globin Gene Variants
- Factors That Lessen the Effects of Mutation
- 12.6 DNA Repair
- Types of DNA Repair
- DNA Repair Disorders
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 13 Introduction
- 13.1 Portrait of a Chromosome
- Required Parts: Telomeres and Centromeres
- Karyotypes Chart Chromosomes
- 13.2 Detecting Chromosomes
- Older Techniques
- Cell-Free Fetal DNA Testing
- Chromosomal Shorthand
- 13.3 Atypical Chromosome Number
- Polyploidy
- Aneuploidy
- Autosomal Aneuploids
- Sex Chromosome Aneuploids: Female
- Sex Chromosome Aneuploids: Male
- 13.4 Atypical Chromosome Structure
- Deletions and Duplications
- Translocation Down Syndrome
- Inversions
- Isochromosomes and Ring Chromosomes
- 13.5 Uniparental Disomy—A Double Dose from One Parent
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 14 Introduction
- 14.1 From Genetics to Genomics
- Beginnings in Linkage and Positional Cloning Studies
- Sequencing the First Human Genomes
- The First Sequenced Human Genomes
- 14.2 The Human Pangenome
- 14.3 Human Genome Content
- Annotation of Genes
- Viral DNA
- Noncoding RNAs
- Repeats
- 14.4 Genomic Medicine
- Shortening the Diagnostic Odyssey
- Increasing Diversity in Genome Databases
- Sequencing the Genomes of the Deceased
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 15 Introduction
- Constant Allele Frequencies
- 15.1 Population Genetics Underlies Evolution
- 15.2 Constant Allele Frequencies
- Hardy-Weinberg Equilibrium
- Solving a Problem Using the Hardy-Weinberg Equation
- 15.3 Applying Hardy-Weinberg Equilibrium
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 16 Introduction
- 16.1 Population Matters: Steel Syndrome in East Harlem
- 16.2 Nonrandom Mating
- 16.3 Migration
- 16.4 Genetic Drift
- The Founder Effect
- Population Bottlenecks
- 16.5 Mutation
- 16.6 Natural Selection
- Negative and Positive Selection
- Dog Breeding Illustrates Artificial Selection
- Antibiotic Resistance Illustrates Natural Selection
- Balanced Polymorphism
- 16.7 Eugenics
- A Brief History of Eugenics
- Designer Babies: Is Prenatal Genetic Testing Eugenic?
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 17 Introduction
- 17.1 Human Origins
- Our Place in the Primate Family Tree
- Archaic Humans
- Modern Humans
- 17.2 Methods to Study Molecular Evolution
- Comparing Genes and Genomes
- Comparing Chromosomes
- Comparing Proteins
- Molecular Clocks
- 17.3 The Peopling of the Planet
- Mitochondrial Eve
- Expansion from Africa
- Populating the New World
- The Great Migration of African Americans
- 17.4 What Makes Us Human?
- Evolution of Human Genomes
- Genes That Help to Define Us
- A Family Tree That Unites All Humankind
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Forensics Focus
- Case Studies and Research Results
- Chapter 18 Introduction
- 18.1 Genetics as an Informational Science
- 18.2 Forensic DNA Typing
- An Evolving Technology
- Using Population Statistics to Interpret DNA Profiles
- Using DNA Profiling to Identify Victims
- Limitations of Forensic DNA Evidence
- Genetic Privacy
- 18.3 Genetic Genealogy
- Mitochondrial and Y Chromosome Haplogroups
- Geographic Origins and Ethnicity Estimates
- Autosomal Haplotypes and Shared Centimorgans
- 18.4 Forensic STRs Meet Genetic Genealogy SNPs
- The Idea to Cross-Reference Information
- Finding a Killer
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Forensics Focus
- Case Studies and Research Results
- Chapter 19 Introduction
- Genetics of Immunity
- 19.1 The Importance of Cell Surfaces
- Blood Groups
- The Major Histocompatibility Complex
- 19.2 The Human Immune System
- Physical Barriers and Innate Immunity
- Adaptive Immunity
- 19.3 Atypical Immunity
- Inherited Immune Deficiencies
- Acquired Immune Deficiency Syndrome
- Autoimmunity
- Allergies
- 19.4 The Immune Response During Pregnancy
- T Regs
- Systemic Sclerosis
- Rh Incompatibility
- 19.5 Altering Immunity
- Vaccines
- Immunotherapy
- Transplants
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 20 Introduction
- 20.1 Cancer Is an Abnormal Growth That Invades and Spreads
- Loss of Cell Cycle Control
- Inherited versus Sporadic Cancer
- 20.2 Cancer at the Cellular Level
- Characteristics of Cancer Cells
- Origins of Cancer Cells
- 20.3 Cancer Genes and Genomes
- Driver and Passenger Mutations
- A Closer Look at Oncogenes
- A Closer Look at Tumor Suppressor Genes
- Environmental Causes of Cancer
- 20.4 Diagnosing and Treating Cancer
- Diagnosing Cancer
- Treating Cancer
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 21 Introduction
- DNA and RNA Technologies
- 21.1 Patenting DNA and RNA
- What Is Patentable?
- Patent Disputes
- 21.2 Modifying DNA
- Constructing and Selecting Recombinant DNA Molecules
- Products from Recombinant DNA Technology
- Transgenic Organisms
- 21.3 Monitoring Gene Function
- 21.4 Gene Silencing and Genome Editing
- Gene Silencing
- Genome Editing
- Gene Drives
- Editing the Human Germline
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 22 Introduction
- 22.1 Genetic Counseling
- 22.2 Genetic Screening and Testing
- Genetic Screening and Testing Through the Human Life Cycle
- A Closer Look at Three Types of Genetic Tests
- 22.3 Treating Genetic Disease
- Protein-Based Therapies
- Gene Therapy
- 22.4 CRISPR-Cas9 in Health Care
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Chapter 23 Introduction
- 23.1 Savior Siblings and More
- 23.2 Infertility and Subfertility
- Infertility in the Male
- Infertility in the Female
- Infertility Tests
- 23.3 Assisted Reproductive Technologies
- Donated Sperm—Intrauterine Insemination
- A Donated Uterus—A Gestational Carrier
- In Vitro Fertilization
- Gamete and Zygote Intrafallopian Transfer
- Oocyte Banking and Donation
- Preimplantation Genetic Diagnosis
- Sequential Polar Body Analysis
- 23.4 Extra Embryos
- Frozen Embryos
- Embryos Used in Research
- Study Guide
- Summary
- Key Terms
- Review Questions
- Critical Thinking Questions
- Case Studies and Research Results
- Answers to key Concepts Questions
- CHAPTER 1
- CHAPTER 2
- CHAPTER 3
- CHAPTER 4
- CHAPTER 5
- CHAPTER 6
- CHAPTER 7
- CHAPTER 8
- CHAPTER 9
- CHAPTER 10
- CHAPTER 11
- CHAPTER 12
- CHAPTER 13
- CHAPTER 14
- CHAPTER 15
- CHAPTER 16
- CHAPTER 17
- CHAPTER 18
- CHAPTER 19
- CHAPTER 20
- CHAPTER 21
- CHAPTER 22
- CHAPTER 23
- Index
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- Figure 18.4 Text Alternative (Chapter 18)
- Figure 18.7 Text Alternative (Chapter 18)
- Figure 18.8 Text Alternative (Chapter 18)
- Figure 18.9a, b Text Alternative (Chapter 18)
- Figure 18.10 Text Alternative (Chapter 18)
- Figure 18.11 Text Alternative (Chapter 18)
- Figure 19A Text Alternative (Chapter 19)
- Figure 19.1 Text Alternative (Chapter 19)
- Figure 19.2 Text Alternative (Chapter 19)
- Figure 19.3 Text Alternative (Chapter 19)
- Figure 19.4 Text Alternative (Chapter 19)
- Figure 19.5 Text Alternative (Chapter 19)
- Figure 19.6 Text Alternative (Chapter 19)
- Figure 19.7 Text Alternative (Chapter 19)
- Figure 19.8 Text Alternative (Chapter 19)
- Figure 19.9 Text Alternative (Chapter 19)
- Figure 19.10 Text Alternative (Chapter 19)
- Figure 19.12 Text Alternative (Chapter 19)
- Figure 19.13 Text Alternative (Chapter 19)
- Figure 19.15 Text Alternative (Chapter 19)
- Figure 19.16 Text Alternative (Chapter 19)
- Figure 19.17 Text Alternative (Chapter 19)
- Figure 19.18 Text Alternative (Chapter 19)
- Figure 19C Text Alternative (Chapter 19)
- Decisions on how Graphic Text Alternative (Chapter 20)
- Figure 20.1 Text Alternative (Chapter 20)
- Figure 20.2a Text Alternative (Chapter 20)
- Figure 20.3 Text Alternative (Chapter 20)
- Figure 20.4 Text Alternative (Chapter 20)
- Figure 20.5 Text Alternative (Chapter 20)
- Figure 20.6 Text Alternative (Chapter 20)
- Figure 20.7 Text Alternative (Chapter 20)
- Figure 20.8 Text Alternative (Chapter 20)
- Figure 20.9 Text Alternative (Chapter 20)
- Figure 20.10 Text Alternative (Chapter 20)
- Figure 20.11 Text Alternative (Chapter 20)
- Figure 20.12a Text Alternative (Chapter 20)
- Figure 20.14 Text Alternative (Chapter 20)
- Figure 20.15 Text Alternative (Chapter 20)
- Figure 20.16 Text Alternative (Chapter 20)
- Figure 20.17 Text Alternative (Chapter 20)
- Figure 20.18 Text Alternative (Chapter 20)
- Figure 20A Text Alternative (Chapter 20)
- Figure 21.2 Text Alternative (Chapter 21)
- Figure 21.3 Text Alternative (Chapter 21)
- Figure 21.4 Text Alternative (Chapter 21)
- Figure 21.5 Text Alternative (Chapter 21)
- Figure 21.6 Text Alternative (Chapter 21)
- Figure 21.7 Text Alternative (Chapter 21)
- Figure 21.8 Text Alternative (Chapter 21)
- Figure 21.9 Text Alternative (Chapter 21)
- Figure 21.10 Text Alternative (Chapter 21)
- Describe a technology Graphic Text Alternative (Chapter 21)
- Figure 22.1 Text Alternative (Chapter 22)
- Figure 22.3 Text Alternative (Chapter 22)
- Figure 22.4 Text Alternative (Chapter 22)
- Figure 22.5 Text Alternative (Chapter 22)
- Figure 22.6 Text Alternative (Chapter 22)
- Figure 22.7 Text Alternative (Chapter 22)
- Figure 22.8 Text Alternative (Chapter 22)
- Figure 23B Text Alternative (Chapter 23)
- Figure 23.2 Text Alternative (Chapter 23)
- Figure 23.3 Text Alternative (Chapter 23)
- Figure 23.5 Text Alternative (Chapter 23)
- Figure 23.6 Text Alternative (Chapter 23)
- Figure 23.7 Text Alternative (Chapter 23)
UM RAFBÆKUR Á HEIMKAUP.IS
Bókahillan þín er þitt svæði og þar eru bækurnar þínar geymdar. Þú kemst í bókahilluna þína hvar og hvenær sem er í tölvu eða snjalltæki. Einfalt og þægilegt!Rafbók til eignar
Rafbók til eignar þarf að hlaða niður á þau tæki sem þú vilt nota innan eins árs frá því bókin er keypt.
Þú kemst í bækurnar hvar sem er
Þú getur nálgast allar raf(skóla)bækurnar þínar á einu augabragði, hvar og hvenær sem er í bókahillunni þinni. Engin taska, enginn kyndill og ekkert vesen (hvað þá yfirvigt).
Auðvelt að fletta og leita
Þú getur flakkað milli síðna og kafla eins og þér hentar best og farið beint í ákveðna kafla úr efnisyfirlitinu. Í leitinni finnur þú orð, kafla eða síður í einum smelli.
Glósur og yfirstrikanir
Þú getur auðkennt textabrot með mismunandi litum og skrifað glósur að vild í rafbókina. Þú getur jafnvel séð glósur og yfirstrikanir hjá bekkjarsystkinum og kennara ef þeir leyfa það. Allt á einum stað.
Hvað viltu sjá? / Þú ræður hvernig síðan lítur út
Þú lagar síðuna að þínum þörfum. Stækkaðu eða minnkaðu myndir og texta með multi-level zoom til að sjá síðuna eins og þér hentar best í þínu námi.
Fleiri góðir kostir
- Þú getur prentað síður úr bókinni (innan þeirra marka sem útgefandinn setur)
- Möguleiki á tengingu við annað stafrænt og gagnvirkt efni, svo sem myndbönd eða spurningar úr efninu
- Auðvelt að afrita og líma efni/texta fyrir t.d. heimaverkefni eða ritgerðir
- Styður tækni sem hjálpar nemendum með sjón- eða heyrnarskerðingu
- Gerð : 208
- Höfundur : 14828
- Útgáfuár : 2020
- Leyfi : 380